Harnessing therapeutic viruses as a delivery vehicle for RNA-based therapy
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چکیده
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چکیده ندارد.
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RNA interference (RNAi) is a ubiquitous pathway that regulates gene expression. It uses small, imperfectly paired, double-stranded RNAs approximately 21 nucleotides long, calledmicroRNAs, that are processed from longer stem-loop transcripts.1 MicroRNAs are taken up by the cytoplasmic RNA-induced silencing complex (RISC), which removes 1 strand, leaving an unpaired strand that binds to messenger...
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ژورنال
عنوان ژورنال: PLOS ONE
سال: 2019
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0224072